![]() Cervical esophageal cancer: a population-based study. Grass GD, Cooper SL, Armeson K, Garrett-Mayer E, Sharma A. Although the cervical esophagus is located adjacent to the SCLNs, the SCLNs may be considered extra-regional lymph nodes in patients with CEC. ![]() The prognosis of the CEC patients with metastatic SCLNs was dismal. The efficacy index was lowest for the lymph nodes in the supraclavicular region. The presence of metastatic SCLNs was a significantly poor prognostic factor ( pā=ā0.004). The pN-positive group with metastatic SCLNs tended to show residual tumor cells and complications after surgery. The 5-year overall survival rate was 58.4% for the pN-negative group, 46.2% for the pN-positive group without metastatic SCLNs, and 7.8% for the pN-positive group with metastatic SCLNs. Of the 67 patients, 23 (34.3%) did not have metastatic lymph nodes (pN-negative group), 27 (40.3%) had metastatic lymph nodes except for metastatic SCLNs (pN-positive group without metastatic SCLN), and 17 (25.4%) had metastatic lymph nodes including metastatic SCLNs (pN-positive group with metastatic SCLNs). These 67 patients were divided into three groups based on the presence of lymph node metastases with or without metastatic SCLNs or the absence of lymph node metastases. Of these patients, 67 underwent radical surgery for CEC. This retrospective study enrolled 835 consecutive patients who underwent radical esophagectomy. This study aimed to investigate whether SCLNs should be considered regional lymph nodes and be dissected in patients with CEC. Few studies have reported on the prognostic impact of SCLN metastases on patients with cervical EC (CEC). The importance of supraclavicular lymph node (SCLN) metastases in esophageal cancer (EC) remains unknown. ![]()
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